目前主要从事中药水溶性活性成分及质量标准研究。先后对罗汉果、木鳖子、玉簪、海龙、荨麻、甜叶菊、榼藤子等中药的药效物质及质量标准进行了较系统研究。发表相关研究论文70余篇,其中SCI收录40篇,获国家发明专利11项,参与编写教材及专著13部,建立国家标准2项。
代表性论著:
[1] Ying Zhang, JinzhaoLiu, Mengyue Wang*, Chenjie Sun, Xiaobo Li*. Five new compounds from Hosta plantaginea flowers and their anti-inflammatory activities [J]. Bioorganic Chemistry,2020,95:10394
[2] Peijun Ju, Wenhua Ding, Jianhua Chen, Ying Cheng, Beibei Yang, Lanting Huang, Qiong Zhou, Cuizhen Zhu, Xiaobo Li, Mengyue Wang*, Jinghong Chen*. The protective effects of Mogroside V and its metabolite 11-oxo-mogrol of intestinal microbiota against MK801-induced neuronal damages [J]. Psychopharmacology, 2020, 237: 1011-1026.
[3] Mengyue Wang, Zhibin Zhan, Ying Xiong, Hao Zhan, Xiaobo Li*. New cytotoxic constituents in the water-soluble fraction from Momordicae Semen [J]. Natural Product Research, 2020, 34 (6): 823-829.
[4] Mengyue Wang, Ying Zhang, Hao Zhang, Xiaoru Feng, Xiaobo Li*. The active glycosides from Urtica fissa rhizome decoction [J]. Journal of Natural Medicine, 2018, 72 (2): 557-562
[5] Mengyue Wang, Ying Peng, Chongsheng Peng, Jiangyuan Qu, Xiaobo Li*. The bioassay-guided isolation of antifungal saponins from Hosta plantaginea leaves [J]. Journal of Asian Natural Products Research, 2018, 20 (6): 501-509
[6] Mengyue Wang, Ying Zhang, Hao Zhang, Xiaoru Feng, Xiaobo Li*.New lignans from Urticae Fissae Herba [J]. Journal of Asian Natural Products Research, 2019, 21 (6): 516–521
[7] Mengyue Wang, Renjie Xu, Ying Peng, Xiaobo Li*, Metabolism analysis of alantolactone and isoalantolactone in rats by oral administration [J]. Journal of Chemistry, https://doi.org/10.1155/2018/2026357
[8] Hao Zhang, Ying Zhang, Mengyue Wang*, Shuo Chen, Xiaobo Li*. The chemical constituents with cytotoxicity from Urtica fissa seed [J]. Journal of Asian Natural Product Research, 2019, 21 (11): 1068-1074
[9] Mengyue Wang, Yan Yang, Xiyan Zhou, Shangshang Wang, Shixin Duan, Xiaobo Li*. The chemical constituents from Urtica fissa leaves [J]. Journal of Asian Natural Products Research, 2018, 20 (8): 709-718
[10] Xiaoru Feng, Mengyue Wang*, Jun Cheng, Xiaobo Li*. Two new secolignans with in vitro anti-inflammatory activities from Urtica fissa rhizomes [J]. Journal of Natural Medicines, 2017, 71 (3): 553-555
[11] Mengyue Wang, Zihan Xu, Ying Peng, Guoyue Zhong, Xiaobo Li*. Two new steroidal saponins with antifungal activity from Hosta plantaginea rhizomes [J]. Chemistry of Natural Compounds, 2016, 52 (6): 1047-1051
[12] Mengyue Wang, Shihua Xing, Thithanhthuy Luu, Min Fan, Xiaobo Li*. The gastrointestinal tract metabolism and pharmacological activities of grosvenorine, a major and characteristic flavonoid in the fruits of Siraitia grosvenorii [J].Chemistry & Biodiversity, 2015, 12 (11): 1652-1663
[13] Shihua Xing1), Mengyue Wang1), Ying Peng, Daofeng Chen, Xiaobo Li*. Simulated gastrointestinal tract metabolism and pharmacological activities of water extract of Scutellaria baicalensis roots [J]. Journal of Ethnopharmacology, 2014, 152 (1): 183-189
[14] Mengyue Wang, Ke Li, Yuxiao Nie, Yingfang Wei, Xiaobo Li*. Antirheumatoid arthritis activities and chemical compositions of phenolic compounds-rich fraction from Urtica atrichocaulis, an endemic plant to China [J]. Evidence-based Complementary and Alternative Medicine, http://dx.doi.org/10.1155/2012/818230
[15] Mengyue Wang, Yuxiao Nie, Ying Peng, Jingyu Yang, Chunfu Wu, Xiaobo Li*. Purification, characterization and antitumor activities of a new protein from Syngnathus acus, an officinal marine fish [J]. Marine Drugs, 2012, 10 (1): 35-50
[16] Mengyue Wang, Sunxing. Qin, Yuxiao Nie, Xiaobo Li*. Bioassay-guided isolation of a novel protein with antitumor activity from Trachyrhamphus serratus (Syngnathidae) [J].Archives of Pharmacal Research, 2011, 34 (6): 893-899
[17] Mengyue Wang, Yunjin He, Yuxiao Nie, Xiaobo Li*. Chemical constituents from the antitumor fraction of Trachyrhamphus serratus [J]. Chemistry of Natural Compounds, 2011, 47 (3): 465-466
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