曾主持或作为科研骨干参加国家自然科学基金、上海市科委基金等,并曾获新疆自治区科技进步一等奖及军队科技进步二等奖等荣誉。
在Biomaterials,ACS Applied Materials & Interfaces,Nanomedicine,Mol Pharm,Int J Pharm等国内外知名杂志上发表研究论文40余篇,申请专利20余项。为研究生开设《生物药剂学》,为本科生开设《药剂学实验》、《中药药剂学》等课程,培养出了多名优秀的博士硕士研究生。
课题组近期主要研究成果:
1. Zhang J, Yang J, Zuo T, Ma S, Xokrat N, Hu Z, Wang Z, Xu R, Wei Y, Shen Q. Heparanase-driven sequential released nanoparticles for ferroptosis and tumor microenvironment modulations synergism in breast cancer therapy. Biomaterials, 2021, 266, 120429.
2. Fang T, Zhang J, Zuo T, Wu G, Xu Y, Yang Y, Yang J, Shen Q. Chemo-Photothermal Combination Cancer Therapy with ROS Scavenging, Extracellular Matrix Depletion, and Tumor Immune Activation by Telmisartan and Diselenide-Paclitaxel Prodrug Loaded Nanoparticles. ACS Appl Mater Interfaces, 2020, 12(28): 31292-308.
3. Zuo T, Li J, Zhang J, Sun L, Liang X, Yang J, Shen Q. Coadministration of chemotherapy and PI3K/Akt pathway treatment with multistage acidity/CathB enzyme-responsive nanocarriers for inhibiting the metastasis of breast cancer. Biomaterials science, 2019, 7(12): 5054-67.
4. Zhang J, Zuo T, Liang X, Xu Y, Yang Y, Fang T, Li J, Chen D, Shen Q. Fenton-reaction-stimulative nanoparticles decorated with a reactive-oxygen-species (ROS)-responsive molecular switch for ROS amplification and triple negative breast cancer therapy. Journal of materials chemistry B, 2019, 7(45): 7141-51.
5. Li J, Liang X, Zhang J, Yin Y, Zuo T, Wang Y, Yang X, Shen Q. Inhibiting pulmonary metastasis of breast cancer based on dual-targeting graphene oxide with high stability and drug loading capacity. Nanomedicine : nanotechnology, biology, and medicine, 2018, 14(4): 1237-48.