Design, synthesis and pre-clinical development of small molecule drug leads
Development of novel formulation
Targeted drug delivery systems
Development of integrative medicine, and Exploratory research on human hibernation.
Publications & Patents
(1)J. P. Collman, L. Fu, P. C. Herrmann, and X. Zhang, “A Functional Model Related to Cytochrome c Oxidase and Its Electrocatalytic Four-Electron Reduction of Dioxygen Science, 1997, 275,949-951.
(2)T. D. Mody, L. Fu, and J. Sessler, “Texaphyrins: Synthesis and Development of A Novel Class of Therapeutic Agents Progress in Inorganic Chemistry, 2001, 551-598.
(3)Z. Wang, L. Fu, and T. D. Mody, “Reaction chemistry of metallotexaphyrins: the synthesis and characterization of the first meso-oxotexaphlorin” Chem. Commun., 2002, 678-679.
(4)J. P. Collman, R. Boulatov, C. Soundland and L. Fu, “Functional Analogs of Cytochrome c Oxidase, Hemoglobin and Myoblobin” Chemical Reviews, 2004, 104, 561-588.
(5)W.H. Wei, Z. Wang, T. Mizuno, C. Cortez, L. Fu, M. Sirisawad, L. Naumovski, D. Magda, J.L.Sessler, “New polyethyleneglycol-functionalized texaphyrins: Synthesis and in vitro biological studies” J. Chem. Soc., Dalton Transactions, 2006, 1934-1942.
(6)Yao Chen，Yingdan Peng, Jiancun Zhang, Lei Fu, “Synthesis and biological evaluation of novel selenonucleosides”Nucleosides, Nucleotides and Nucleic Acids, 2008,27,1001-1008
(7)Wenlu Liu，Jiancun Zhang，Faqin Jiang, Lei Fu, “Synthesis and Cytotoxicity Studies of New Cryptophycin Analogues” Arch. Pharm. Chem. Life Sci. 2009, 342, 577 – 583
(8)Wenlu Liu，Faqin Jiang, Jingbao Liu, Jiancun Zhang，Lei Fu*, “Synthesis of bis-ANS fluorescence probe in ionic liquids”Chinese Chemical Letters, 20 (2009) 645–647
